St. Louis To Deal Kansas City A Loss Wednesday

Chris Wassel
By , Updated on: Jun 4, 2025 12:00 AM
OSB St. Louis To Deal Kansas City A Loss Wednesday
  • When: Wednesday, June 4th at 7:45 PM ET
  • Who: Kansas City Royals vs St. Louis Cardinals
  • TV/Streaming: MLB.tv
  • Starting Pitchers: Noah Cameron and Miles Mikolas
  • Where: Busch Stadium in St. Louis, Missouri

The St. Louis Cardinals entertain the St. Louis Cardinals from iconic Busch Stadium on Wednesday night. Yes, both teams are battling for a wildcard spot this could be an unexpectedly fun matchup. Now Royals vs Cardinals bets examine this matchup between two squads who have a lot to play for.

The Cardinals are currently the favorite on Wednesday mostly on the strength of home field advantage and due to the motivation of revenge. While the Royals stole a game on Tuesday, St. Louis wants to get that win on Wednesday to stay within shouting distance of the Chicago Cubs in the National League Central. Meanwhile, Kansas City is chasing Detroit in the American League Central.

Go check out those betting on the National League online, it is important to note that St. Louis is 19-9 at home and can score around five runs a game.

So, with this second game of the series almost here, let us get rolling!

A Time To Set The Table

The Royals vs Cardinals bets knows it is time to set the table. Yes, bettors set their sights on the game totals and the moneyline However, the weather remains a huge concern given the humidity. Unfortunately, the weather in St. Louis expects to feature a steady diet of scattered thunderstorms and temperatures in the 70's for the game. Now, here are those numbers.

MLB Wednesday Night Bovada BetOnline BetUS
Kansas City Royals +110 +110 +115
St. Louis Cardinals -130 -130 -135
Over 8.5 Runs -105 -106 -105
Under 8.5 Runs -125 -127 -125

Many want to know whether St. Louis can really challenge the Chicago Cubs. That is no easy task this year. However, St. Louis has pitching going for itself and some solid team defense. The Cardinals allow around 3.7 runs a game and that number drops to 3.5 at home. It was why when Kansas City popped in for 10 runs on Tuesday, that was quite a surprise. Not only did the two teams combine for 17 runs, the bettors were left wondering okay what is next.

Despite that, St. Louis has the home-field advantage, a slight pitching advantage, and some moisture to help them out on Wednesday. Can they take advantage of it? All signs point to yes even with Kansas City starting a rookie who is no ordinary rookie. Also, in the event this game gets postponed, expect this game to be moved to Thursday afternoon as part of a day-night doubleheader.

St. Louis Cardinals To win on Wednesday night
Bovada
-130

More Royals vs Cardinals Bets For Wednesday Night

Yes, the Royals vs Braves bets have more to offer for Wednesday night. The St. Louis Cardinals send out veteran Miles Mikolas on the mound. At this stage of his career, Mikolas gives the Cardinals a solid 5-6 innings before the bullpen takes over. He will want to rebound after a nightmarish start in Baltimore that saw him go four innings and get shelled for four runs on nine hits. The Orioles knocked him around. Fortunately, this game is in St. Louis and Mikolas has won three of his past four starts.

The one worry for the Cardinals pitcher may be the lack of strikeouts. Mikolas is very crafty and has to be these days. He never was much of a strikeout pitcher but now his 5.5 K/9 is the lowest in his long career. Kansas City batters are aggressive and will be desperate to try and continue their offensive momentum. Mikolas is up for the challenge, however and so is the Cardinals' bullpen.

Betting on the Cardinals to cover could prove to be a winning strategy. One is banking on St. Louis scoring a few more runs than usual against a rookie. Also, St. Louis has one of the better bullpens in the National League. More importantly is the reality that the Cardinals cannot afford to get too far back even in the wildcard race. Their run differential of almost 0.8 at home makes this worth a look.

St. Louis Cardinals To beat Kansas City by 2+ runs Wednesday
BetUS
+165

Wednesday Night And The Game Total

The Royals vs Cardinals bets consider the Wednesday night game total. With the 8.5 number, the temptation on the over is very easy given what happened on Tuesday night. Who could blame the bettor? Again, 17 runs is a lot for these two teams. That is all more the reason to pivot to the under side here. Noah Cameron could get shelled in this "Battle Of Missouri" but the rookie has been creative in his first four starts. He has been stellar allowing only three runs in almost 26 innings pitched.

There is the feeling that some nerves will be there for Cameron. It is a huge spot. However, the former prospect seems ready to handle the challenge. With Mikolas pitching for St. Louis, two crafty pitchers who know how to take advantage of a ballpark like Busch Stadium help here. Also, both bullpens have been pretty good all season. Expect quite a little chess match early and then late in this tilt.

Yes, I am riding with the under of 8.5 runs at -125 odds with BetUS. 

Kansas City and St. Louis To score fewer than 8 runs on Wednesday night
BetUS
+102

Go examine those top online sportsbook reviews, like the BetUS online review for the current MLB numbers on your favorite games before placing some bets. And yes, check the weather too!

Meet the author

Chris Wassel

Chris Wassel AA, AAS CURRENTLY Sports Writer and Journalist RESIDES IN Rahway, NJ EDUCATION Union County College, Montclair State University EXPERTISE Business, Writing, Sports, Food, Grilling, Olympics, Injuries, Politics, and Baking Cookies Summary A long s...

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